Systemic candidiasis is a fungal infection that results from an overgrowth and spread of Candida (yeast) in body tissues. The 'passage' of Candida albicans (pathogens) through the gastrointestinal mucosa in the bloodstream is seen as an important mechanism for the development of systemic candidiasis. Systemic Candidiasis can be accompanied by symptoms such as migraine headache, depression, urogenital dysfunction, gas formation the intestines and allergies. In more extreme cases, the patient feels completely 'paralyzed'.
When Candida albicans or antigens thereof pass through the gastrointestinal mucosa and enter the blood, the formation of specific antibodies against this fungal yeast. At the first contact, the formation of antibodies of the IgM type. This is later followed by the synthesis of antibodies of the IgG type.
Infection of the (intestinal) mucosa stimulates the production of IgA antibodies. The test measures all three types of antibodies against Candida albicans in serum: IgG, IgA and IgM. The titers of these antibodies in combination with the complaint pattern provide information about the possible presence of a systemic Candidiasis and the 'location' and phase thereof.